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K.A. SCIENCE TECHNOLOGY Co.,Ltd.


Our company is the global brand distributor of laboratory instrument and equipment such as PerkinElmer (FTIR, ICP-OES, GC, HPLC, AAS etc.), Horiba (RAMAN, Particle Size Analyzer), Thermo Scientific (Freezer, Centrifuge, Biosafety Cabinet), Memmert (Oven, Incubator, Water bath), OHAUS (Analytical Balance, Precision Balance), Lovibond (Water Testing, Color Measurement) and others. We also have after sale service including repairing, calibration and maintenance for all laboratory instrument and equipment by specialized technician. 

In addition, we can provide full of laboratory service including design and installation laboratory furniture, exhaust system, gas system, electrical system. All of process are controlled by expert engineer.

 

PerkinElmer new LC system

Qsight@ Triple Quad (UHPLC-MSMS)
LC-MSMS Chemistry: Develop a Sensitive Method for Cannabis & Hemp Pesticides
Pesticide Analysis in Cannabis is Challenging
✓ Complex matrix associated with Cannabis plant material and edibles needs to be addressed.
✓ Broad Interference from Cannabinoids present in 10-20 %(100000-200000 ppm) range.
✓ Terpenes and other non-cannabinoids compounds are present in high ppm (10-5000 ppm).
✓ Pesticides in 1.0-1000 ppb (0.00001-0.00010 %).

1. Pesticide and Fungicides
2. Mycotoxin Analysis
3. Bioactive Compounds (Canabinoids analogue) analysis
  

 

 การหาโลหะหนัก ใน กัญชง กัญชา โดยเครื่อง ICP-MS

        Owing to the toxicity of heavy metals, it is increasingly important to test cannabis flowers and other cannabis derivatives so that patient and consumer safety is maintained as the use of cannabis becomes more common. This need has translated into an increasing demand for testing cannabis flowers and other cannabis derivatives for toxins such as the heavy metals cadmium (Cd), lead (Pb), arsenic (As), and mercury (Hg). Similar to federal pharmaceutical and nutraceutical requirements in the US1-5, states like California6, Oregon, and Colorado have published action limits for heavy metals.
Each jurisdiction where cannabis is permitted has published required maximum allowable heavy metals in cannabis and related products. Many of these limits are based on USP <232>/ICH Q3D recommendations. The limits differ based on the route of administration, similarly to what is set out in the ICH Q3D recommendations. Currently, Canada has not set regulations around metals in cannabis products, but is referring to USP <232> and <233> for guidance. Some of the currently known limits for heavy metals are provided in Table 1. For the purpose of this study, the California limits on “all inhaled cannabis goods” were used as they are the most stringent and most applicable to cannabis flower.
 

 

 

 

 

cosmetic products analyzed by confocal Raman spectroscopy

Pharmaceutical compounds distribution and cosmetic products analyzed by confocal Raman spectroscopy

 

During pharmaceutical and cosmetic formulation process, an important step is in the control of the distribution of the compounds once the product is designed in its final state. For example, in a pharmaceutical tablet, the size and distribution controls over a large area of the tablet are important for drug release control. That can be also applied on liquid products, like a nasal spray or oral suspensions. It also concerns the emulsions and creams commonly proposed by cosmetic companies.

In that case, the point of interest is in the analysis of the distribution of the compounds after the application of the cream. In order to simulate skin, cosmetic manufacturers commonly use some rough PMMA slides.

This step in the control process is required so a technique is able to chemically characterize the product as they are, in a non-invasive and non-destructive manner. Thus, vibrational spectroscopies are well designed for such characterization. Moreover, confocal Raman microscopy is the perfect tool for this.

Get to link : https://www.horiba.com/bra/applications/health-care/pharmaceuticals-and-medicine-manufacturing/pharmaceutical-compounds-distribution-and-cosmetic-products-analyzed-by-confocal-raman-spectroscopy/ 

 

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